| Description | FDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6(FDI6) binds to the FOXM1 protein and specifically downregulates FOXM1-activated genes. |
| In vitro | FDI-6特异性下调了FOXM1激活的基因，这些基因的FOXM1占据通过ChIP-PCR得到确认。这种小分子介导的效应专门针对FOXM1控制的基因，对同源叉头框家族因子调节的基因没有影响。 |
| Synonyms | FDI6, FDI 6 |
| molecular weight | 437.43 |
| Molecular formula | C19H11F4N3OS2 |
| CAS | 313380-27-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 50 mg/mL (114.3 mM) |
| References | 1. Gormally MV., et al. Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition. Nat Commun. 2014 Nov 12;5:5165. |