| Description | FATP1-IN-2 is a fatty acid transporter protein 1 (FATP1) inhibitor with oral activity for the study of obesity and metabolic diseases. |
| In vivo | FATP1-IN-2（10 mg/kg；口服；小鼠）的 Cmax 值高于小鼠 IC50 值。[1]FATP1-IN-2（3、10、30 mg/kg；口服；持续 4 周；小鼠）在任何剂量下均未显示各组织中的 TG 含量发生变化。[1] |
| Target activity | FATP1 (human):0.43 μM, FATP1 (mouse):0.39 μM |
| molecular weight | 353.39 |
| Molecular formula | C19H20FN5O |
| CAS | 2650944-83-3 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 80 mg/mL (226.38 mM), Sonication is recommended. |
| References | 1. Matsufuji T, et al. Arylpiperazines as fatty acid transport protein 1 (FATP1) inhibitors with improved potency and pharmacokinetic properties. Bioorg Med Chem Lett. 2013;23(9):2560-2565. |