| Description | Ethyl potassium malonate, a competitive inhibitor of the enzyme succinate dehydrogenase, acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation and serves as an intermediate for the preparation of ethyl tert-butyl malonate. |
| Synonyms | Potassium 3-ethoxy-3-oxopropanoate, Malonic Acid Monoethyl Ester Potassium Salt, 丙二酸单乙酯钾盐 |
| molecular weight | 170.21 |
| Molecular formula | C5H7KO4 |
| CAS | 6148-64-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | H2O: 30 mg/mL (176.26 mM) |
| References | 1. Lee JH, et al. The decarboxylative Blaise reaction. J Org Chem. 2007 Dec 21;72(26):10261-3. doi: 10.1021/jo701743m. Epub 2007 Nov 30. |