| Description | Ethoproprazine hydrochloride is an butyrylcholinesterase inhibitor. It reduces extrapyramidal motor effects and used as an antidyskinetic, characteristic of Parkinson′s disease. It also alleviates thermal hyperalgesia in rats. |
| Synonyms | Lysivane, Parphezein, Dibutil, Parfezin, Profenamine HCl, Pardisol |
| molecular weight | 348.93 |
| Molecular formula | C19H25ClN2S |
| CAS | 1094-08-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | H2O: Insoluble DMSO: Soluble |
| References | 1. MITCHELL RG. Ethopropazine hydrochloride in treatment of cerebral palsy. Br Med J. 1953 Jun 13;1(4823):1313-5. PubMed PMID: 13042233; PubMed Central PMCID: PMC2016592. 2. Masti SP, Seetharamappa J, Melwanki MB. Extractive spectrophotometric determination of tungsten(VI) in alloy steels using ethopropazine hydrochloride. Anal Sci. 2002 Aug;18(8):913-5. PubMed PMID: 12200839. 3. Tvarijonaviciute A, Ceron JJ, Tecles F. Acetylcholinesterase and butyrylcholinesterase activities in obese Beagle dogs before and after weight loss. Vet Clin Pathol. 2013 Jun;42(2):207-11. doi: 10.1111/vcp.12032. Epub 2013 Apr 1. PubMed PMID: 23550593. 4. Bahar FG, Imai T. Aspirin hydrolysis in human and experimental animal plasma and the effect of metal cations on hydrolase activities. Drug Metab Dispos. 2013 Jul;41(7):1450-6. doi: 10.1124/dmd.113.051805. Epub 2013 May 6. PubMed PMID: 23649702. |