| Description | Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.Esomeprazole magnesium acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H+-ATPases |
| Synonyms | (S)-Omeprazole magnesium, NEXIUM, 埃索美拉唑镁, (-)-Omeprazole magnesium |
| molecular weight | 713.12 |
| Molecular formula | C34H36MgN6O6S2 |
| CAS | 161973-10-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | Ethanol: 143 mg/mL (200.52 mM) H2O: < 1 mg/mL (insoluble or slightly soluble) DMSO: 45 mg/mL (63.1 mM) |
| References | 1. Kumar P, et al. Drug Deliv Transl Res. 2015 Jun;5(3):243-56. |