| Description | Erythromycin thiocyanate acts by binding to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid .Erythromycin thiocyanate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. |
| In vitro | Erythromycin inhibits growth of P. falciparum with IC50 and IC90 values of 58.2 μM and 104.0 μM, respectively. |
| molecular weight | 793.02 |
| Molecular formula | C38H68N2O13S |
| CAS | 7704-67-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Gribble MJ, et al. Erythromycin. Med Clin North Am. 1982 Jan;66(1):79-89. 2. Nakornchai S, et al. Activity of azithromycin or erythromycin in combination with antimalarial drugs against multidrug-resistant Plasmodium falciparum in vitro. Acta Trop. 2006 Dec;100(3):185-91. Epub 2006 Nov 28. |