| Description | ERCC1-XPF-IN-1 is a potent, high-affinity inhibitor of ERCC1-XPF (IC50: 0.49 μM). ERCC1-XPF-IN-1 inhibits the removal of CPDs, reduces the toxicity of cyclophosphamide to colorectal cancer cells, enhances the cytotoxic effects of UV radiation, and impedes DNA repair. |
| molecular weight | 506.04 |
| Molecular formula | C28H32ClN5O2 |
| CAS | 2411584-25-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |