| Description | Endixaprine (SR 41378) is a small molecule compound used to treat neurological disorders and may be used to study anxiety disorders and epilepsy. |
| In vivo | 在小鼠中通过口服给药方式，Endixaprin 表现出抗惊厥活性，其在强直性癫痫中的半数有效剂量为11 mg/kg。[1] |
| Synonyms | SR 41378 |
| molecular weight | 324.21 |
| Molecular formula | C15H15Cl2N3O |
| CAS | 93181-85-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 45 mg/mL (138.8 mM) |
| References | 1. Hallot A, et al. Synthesis and activity of 6-aryl-3-(hydroxypolymethyleneamino)pyridazines in animal models of epilepsy. J Med Chem. 1986;29(3):369-375. |