| Description | EM-651 (2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-, (2R)-) is an enantiomer of EM-652, IC50=20.0 nM. EM-652 is an orally active pure antiestrogen and selective estrogen receptor antagonist, IC50=0.44nM. |
| Synonyms | 2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-, (2R)- |
| molecular weight | 457.56 |
| Molecular formula | C29H31NO4 |
| CAS | 182167-58-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 45 mg/mL (98.35 mM) |
| References | 1. Martel C, Provencher L, Li X, St Pierre A, Leblanc G, Gauthier S, Mérand Y, Labrie F. Binding characteristics of novel nonsteroidal antiestrogens to the rat uterine estrogen receptors. J Steroid Biochem Mol Biol. 1998 Feb;64(3-4):199-205. doi: 10.1016/s0960-0760(97)00192-1. PMID: 9605415. |