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ELOVL6-IN-2

CAS No.: 1067647-43-1

ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.
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Description ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.
In vivo ELOVL6-IN-2 在小鼠肝脏中有效且成比例地抑制了脂肪酸的延长指数[1]。
Target activity ELOVL6:34 nM(mouse )
molecular weight 579.49
Molecular formula C28H23F6N3O4
CAS 1067647-43-1
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility DMSO: 90 mg/mL (155.31 mM), Sonication is recommended.
References 1. Synthesis and evaluation of a novel indoledione class of long chain fatty acid elongase 6 (ELOVL6) inhibitors.[J]. Journal of Medicinal Chemistry, 2009, 52(10):3142.