| Description | Elobixibat (A 3309) is an inhibitor of the ileal bile acid transporter (IC50: 0.13 nM, 0.53 nM, and 5.8 nM for mouse, human, and canine IBAT). Elobixibat can be used in studies about chronic idiopathic constipation. |
| Target activity | IBAT (human):0.53 nM, IBAT (canine):5.8 nM, IBAT (mouse):0.13 nM |
| Synonyms | AZD 7806, A 3309 |
| molecular weight | 695.89 |
| Molecular formula | C36H45N3O7S2 |
| CAS | 439087-18-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 225.0 mg/mL (323.3 mM), Sonication is recommended. |
| References | 1. Wong BS, et al. Elobixibat for the treatment of constipation. Expert Opin Investig Drugs. 2013 Feb; 22(2):277-84. |