| Description | EGFR-IN-1 TFA is an orally active and irreversible L858R/T790M mutant selective EGFR inhibitor. EGFR-IN-1 TFA potently inhibits Gefitinib-resistant EGFR L858R, T790M with 100-fold selectivity over wild-type EGFR . EGFR-IN-1 TFA displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity [1] . |
| molecular weight | 628.6 |
| Molecular formula | C30H31F3N6O6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |