| Description | EGA inhibits the intoxication of lethal toxins and prevents the entry of a variety of other acid-dependent bacterial toxins and viruses into mammalian cells.EGA is a powerful tool for the study of membrane trafficking and can be used to treat infectious diseases. |
| molecular weight | 346.22 |
| Molecular formula | C16H16BrN3O |
| CAS | 415687-81-9 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 5 mg/mL (11.22 mM), Sonication is recommended. |
| References | 1. Gillespie EJ, et al. Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):E4904-12. 2. Bergin RJ, Emery J, Bollard RC, Falborg AZ, Jensen H, Weller D, Menon U, Vedsted P, Thomas RJ, Whitfield K, White V. Rural-urban disparities in time to diagnosis and treatment for colorectal and breast cancer. Cancer Epidemiol Biomarkers Prev. 2018 Jul 9. pii: cebp.0210.2018. doi: 10.1158/1055-9965.EPI-18-0210. [Epub ahead of print] PubMed PMID: 29987098. 3. Simpong DL, Awuku YA, Kye-Amoah KK, Morna MT, Adoba P, Anin SK, Adu P. High Iodine Deficiency among Pregnant Women in Periurban Ghana: A Hospital-Based Longitudinal Study. J Nutr Metab. 2018 Jun 3;2018:9706805. doi: 10.1155/2018/9706805. eCollection 2018. PubMed PMID: 29967696; PubMed Central PMCID: PMC6008623. 4. Lusito E, Felice B, D'Ario G, Ogier A, Montani F, Di Fiore PP, Bianchi F. Unraveling the role of low-frequency mutated genes in breast cancer. Bioinformatics. 2018 Jun 29. doi: 10.1093/bioinformatics/bty520. [Epub ahead of print] PubMed PMID: 29961866. |