| Description | Ecabapide (DQ-2511) is a novel gastrointestinal motility promoter that significantly enhances gastric emptying in SHRSP.Ecabapide activates cyclic GMP-dependent housekeeping Cl- channels in rabbit gastric wall cells. |
| Synonyms | DQ2511, DQ 2511, DQ-2511 |
| molecular weight | 371.43 |
| Molecular formula | C20H25N3O4 |
| CAS | 104775-36-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Furuhama K,et al. Pharmacology of the gastric pro-kinetic drug ecabapide (DQ-2511). J Pharm Pharmacol. 1997 Dec;49(12):1168-74. doi: 10.1111/j.2042-7158.1997.tb06064.x. PMID: 9466337. 2. Furuhama K. Ecabapide, a novel gastroprokinetic agent, ameliorates gastric emptying of stroke-prone spontaneously hypertensive rats (SHRSP). J Vet Med Sci. 1997 Dec;59(12):1153-5. 3. Sakai H, et al. A cyclic GMP-dependent housekeeping Cl- channel in rabbit gastric parietal cells activated by a vasodilator ecabapide. Br J Pharmacol. 1996 Dec;119(8):1591-9. 4. Hatanaka S,et al. Possible mechanisms underlying the suppression of gastric vagal afferents due to ecabapide (DQ-2511), a gastroprokinetic agent, in rats. Jpn J Pharmacol. 1997 May;74(1):105-8. |