| Description | Duloxetine D3 hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for the treatment of major depressive disorder and generalized anxiety disorder (GAD). Duloxetine D3 hydrochloride ((S)-Duloxetine D3 hydrochloride) is a deuterium-labeled Duloxetine hydrochloride. |
| Synonyms | (S)-Duloxetine D3 hydrochloride, LY248686 D3 hydrochloride |
| molecular weight | 336.89 |
| Molecular formula | C18H20ClNOS |
| CAS | 1435727-97-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. De Berardis, D., et al., The effect of newer serotonin-noradrenalin antidepressants on cytokine production: a review of the current literature. Int J Immunopathol Pharmacol, 2010. 23(2): p. 417-22. 2. Wang, S.Y., J. Calderon, and G. Kuo Wang, Block of neuronal Na+ channels by antidepressant duloxetine in a state-dependent manner. Anesthesiology, 2010. 113(3): p. 655-65. |