| Description | DTT (DL-Dithiothreitol) is a reagent for maintaining SH groups in the reduced state. |
| Synonyms | 二硫苏糖醇, DL-Dithiothreitol |
| molecular weight | 154.25 |
| Molecular formula | C4H10O2S2 |
| CAS | 3483-12-3 |
| Storage | store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | H2O: 200 mg/mL (1296.60 mM) DMSO: 45 mg/mL (291.73 mM), Sonication is recommended. |
| References | 1. Sears DW, et al. Relative susceptibilities of the interchain disulfides of an immunoglobulin G molecule to reduction by dithiothreitol. Biochemistry. 1977 May 3;16(9):2031-5. |
| Citations | 1. Wang J K, Li Y, Zhao X L, et al. Ablation of Plasma Prekallikrein Decreases LDL Cholesterol by Stabilizing LDL Receptor and Protects against Atherosclerosis. Circulation. 2022;145:675–687 2. Wang J K, Li Y, Zhao X L, et al. Ablation of Plasma Prekallikrein Decreases LDL Cholesterol by Stabilizing LDL Receptor and Protects Against Atherosclerosis. Circulation. 2022 |