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Drimane

CAS No.: 5951-58-6

Drimane is a bicyclic sesquiterpene. It is the parent structure of many natural products with various biological activit
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Description Drimane is a bicyclic sesquiterpene. It is the parent structure of many natural products with various biological activity.
molecular weight 208.389
Molecular formula C15H28
CAS 5951-58-6
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Gonçalves GEG, Morais TR, Gomes KS, Costa-Silva TA, Tempone AG, Lago JHG, Caseli L. Antitrypanosomal activity of epi-polygodial from Drimys brasiliensis and its effects in cellular membrane models at the air-water interface. Bioorg Chem. 2018 Nov 24;84:186-191. doi: 10.1016/j.bioorg.2018.11.048. [Epub ahead of print] PubMed PMID: 30502630. 2. Kou RW, Du ST, Li YX, Yan XT, Zhang Q, Cao CY, Yin X, Gao JM. Cyathane diterpenoids and drimane sesquiterpenoids with neurotrophic activity from cultures of the fungus Cyathus africanus. J Antibiot (Tokyo). 2019 Jan;72(1):15-21. doi: 10.1038/s41429-018-0106-3. Epub 2018 Oct 16. PubMed PMID: 30327549. 3. De La Chapa J, Singha PK, Sallaway M, Self K, Nasreldin R, Dasari R, Hart M, Kornienko A, Just J, Smith JA, Bissember AC, Gonzales CB. Novel polygodial analogs P3 and P27: Efficacious therapeutic agents disrupting mitochondrial function in oral squamous cell carcinoma. Int J Oncol. 2018 Dec;53(6):2627-2636. doi: 10.3892/ijo.2018.4585. Epub 2018 Oct 5. PubMed PMID: 30320372; PubMed Central PMCID: PMC6203145. 4. Ma M, Feng J, Wang D, Chen SW, Xu H. Synthesis and Antifungal Activities of Drimane-Amide Derivatives from Sclareol. Comb Chem High Throughput Screen. 2018;21(7):501-509. doi: 10.2174/1386207321666180925164358. PubMed PMID: 30255746.