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DPTA NONOate

CAS No.: 146724-95-0

DPTA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of thre
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Description DPTA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of three hours and five hours at 37°C and 22-25°C, pH 7.4, respectively, to liberate 2 moles of NO per mole of parent compound. [1][2]
Synonyms Dipropylenetriamine NONOate
molecular weight 191.23
Molecular formula C6H17N5O2
CAS 146724-95-0
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility H2O: Highly Soluble
References 1. Hrabie, J.A., Klose, J.R., Wink, D.A., et al. New nitric oxide-releasing zwitterions derived from polyamines. The Journal of Organic Chemistry 58, 1472-1476 (1993). 2. Keefer, L.K., Nims, R.W., Davies, K.M., et al. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms. Methods in Enzymology 268, 281-293 (1996).