| Description | DprE1-IN-7 (Compound 64) is a DprE1 inhibitor with potent anti-tuberculosis (TB) activity, demonstrating a minimum inhibitory concentration (MIC) of 1 μM against the Mtb H37Rv strain. It exhibits antimycobacterial effects on drug-resistant strains. Additionally, DprE1-IN-7 shows high microsomal stability and exhibits medium clearance [1]. |
| molecular weight | 360.41 |
| Molecular formula | C20H20N6O |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |