| Description | DNA-PK-IN-4 (WO2021209055A1, compound 27), an imidazolinone derivative compound, is a highly effective inhibitor of DNA-PK, specifically targeting DNA-PKcs activity. By inhibiting DNA-PKcs, the compound significantly impairs tumor DNA repair mechanisms and triggers apoptosis in cells. With its potential application in cancer research, DNA-PK-IN-4 holds promise for further investigation [1]. |
| molecular weight | 396.44 |
| Molecular formula | C20H24N6O3 |
| CAS | 2722645-10-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |