| Description | DN02 is a selective and efficient probe for the bromodomain of BRD8.DN02 has an affinity for BRD8 (1) and BRD8 (2). |
| In vitro | DN02 在 AlphaScreen 生化实验中具有低至 nM 的 IC50值（48 nM），对 BRD9 和 BRD4 具有高度选择性[1]。 |
| Target activity | EED Alphascreen:48 nM |
| molecular weight | 397.44 |
| Molecular formula | C22H24FN3O3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 2 mg/mL (5.03 mM), Sonication is recommended. |
| References | 1. Remillard D, et al. Chemoproteomics Enabled Discovery of Selective Probes for NuA4 Factor BRD8. ACS Chem Biol. 2021 Nov 19;16(11):2185-2192. |