| Description | DMNQ is a 1,4-naphthoquinone that acts as a redox-cycling agent, typically increasing intracellular superoxide and hydrogen peroxide formation.DMNQ increases ROS generation |
| In vivo | DMNQ的应用能够改变多种细胞参数，包括信号传导、线粒体功能和基因表达[1,2]。 |
| molecular weight | 218.21 |
| Molecular formula | C12H10O4 |
| CAS | 6956-96-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: < 1 mg/mL (insoluble or slightly soluble) DMSO: 2.18 mg/mL (10 mM) |
| References | 1. The Bioenergetic Health Index is a sensitive measure of oxidative stress in human monocytes[J]. Redox Biology, 2016, 8:43-50. 2. Shi M M . Quinone-induced oxidative stress elevates glutathione and induces gamma-glutamylcysteine synthetase activity in rat lung epithelial L2 cells[J]. Journal of Biological Chemistry, 1994, 269(42):26512-26517. |