| Description | DL-Metanephrine-d3 Hydrochloride is L-Metanephrine labeled with deuterium atoms and can be used to study the metabolic flow of L-Metanephrine in the body. |
| In vitro | 在某些情况下，氘代化合物可能比非氘代化合物具有优势，通常是通过清除率的改变。氘化还可以将代谢途径重新定向到减少毒性的方向。其他氘代化合物的批准可能很快就会随之而来。临床医生需要熟悉这些新实体的剂量、疗效、潜在副作用和独特的代谢特征。[2] |
| molecular weight | 236.71 |
| Molecular formula | C10H13D3ClNO3 |
| CAS | 1085333-94-3 |
| Storage | keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 years | Shipping with blue ice. |
| References | 1. Yanjiao X,et al. Evaluation of the inhibitory effects of antihypertensive drugs on human carboxylesterase in vitro. Drug Metab Pharmacokinet. 2013;28(6):468-74. doi: 10.2133/dmpk.dmpk-12-rg-143. 2. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. |
DL-Metanephrine-d3 Hydrochloride
CAS No.: 1085333-94-3
DL-Metanephrine-d3 Hydrochloride is L-Metanephrine labeled with deuterium atoms and can be used to study the metabolic f
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