| Description | DIPQUO hydrochloride is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO hydrochloride promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β. |
| In vitro | 在C2C12成肌细胞裂解液中通过荧光发射测定法测量ALP活性，作为对ALP底物酶解的报告指标的DIPQUO的EC50为6.27 μM[1]。 |
| Synonyms | DIPQUO hydrochloride(1269365-82-3 Free base) |
| molecular weight | 351.83 |
| Molecular formula | C20H18ClN3O |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (142.11 mM) |
| References | 1. Cook B, et al. Discovery of a Small Molecule Promoting Mouse and Human Osteoblast Differentiation via Activation of p38 MAPK-β. Cell Chem Biol. 2019 Mar 29. |