| Description | Diapocynin (Dehydrodiacetovanillone), a dimer of Apocynin, acts as an orally administered inhibitor of NADPH oxidase. It exhibits anti-inflammatory, neuroprotective, and antioxidant properties [1]. |
| In vivo | Diapocynin（300 mg/kg；口服；每12小时一次，连用72小时）能有效缓解DFP诱发的运动障碍，并减少DFP治疗后72小时内的癫痫样发作频率。此外，Diapocynin显著降低了DFP所引起的反应性星形胶质细胞增殖、神经细胞变性、GP91phox水平上升、谷胱甘肽减少、血清亚硝酸盐增高及促炎细胞因子和趋化因子（如IL-1α、IL-6、IL-2、IL-17A、瘦素、IP-10[1]）的水平。 |
| Synonyms | Dehydrodiacetovanillone |
| molecular weight | 330.33 |
| Molecular formula | C18H18O6 |
| CAS | 29799-22-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |