| Description | DFHO is a Corn homologous ligand that fluoresces yellow upon excitation and is used to image RNA in living cells. |
| Target activity | Corn-DFHO:70 nM (Kd) |
| molecular weight | 281.21 |
| Molecular formula | C12H9F2N3O3 |
| CAS | 1420815-34-4 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 80 mg/mL (284.48 mM), Sonication is recommended. |
| References | 1. Wenjiao Song, et al. Imaging RNA polymerase III transcription using a photostable RNA-fluorophore complex. Nat Chem Biol. 2017 Nov;13(11):1187-1194. 2. Hyaeyeong Kim, et al. A Fluorogenic RNA-Based Sensor Activated by Metabolite-Induced RNA Dimerization. Cell Chem Biol. 2019 Dec 19;26(12):1725-1731.e6. |