| Description | Deoxybenzoin (2-Phenylacetophenone) is used to target immune sensors and xanthine oxidase. It is used for the treatment of gout. |
| Synonyms | 二苯基乙酮, 2-Phenylacetophenone, Benzyl phenyl ketone, NSC-131456, NSC131456, NSC 131456 |
| molecular weight | 196.24 |
| Molecular formula | C14H12O |
| CAS | 451-40-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 60 mg/ml (305.75 mM) |
| References | 1. Huang J, Zhou Z, Zhou M, Miao M, Li H, Hu Q. Development of benzoxazole deoxybenzoin oxime and acyloxylamine derivatives targeting innate immune sensors and xanthine oxidase for treatment of gout. Bioorg Med Chem. 2018 May 1;26(8):1653-1664. 2. Timofeeva DS, Mayer RJ, Mayer P, Ofial AR, Mayr H. Which Factors Control the Nucleophilic Reactivities of Enamines? Chemistry. 2018 Apr 17;24(22):5901-5910. 3. Moskvina VS, Shablykina OV, Khilya VP. Reactions of 3-Arylisocoumarins with N-Nucleophiles - A Route to Novel Azaheterocycles. Curr Top Med Chem. 2017;17(29):3199-3212. 4. Srinivasan B, Rodrigues JV, Tonddast-Navaei S, Shakhnovich E, Skolnick J. Rational Design of Novel Allosteric Dihydrofolate Reductase Inhibitors Showing Antibacterial Effects on Drug-Resistant Escherichia coli Escape Variants. ACS Chem Biol. 2017 Jul 21;12(7):1848-1857. |