| Description | Deox B 7,4 is a reversible microtubule inhibitor that acts by increasing lysosomal V-ATPase activity and lysosome acidity. |
| Synonyms | Deoxysappanone-B-7,4 dimethyl ether, Deox-B-7,4, Deoxysappanone B 7,4 dimethyl ether, DeoxB7,4 |
| molecular weight | 314.33 |
| Molecular formula | C18H18O5 |
| CAS | 674786-37-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Bernard D, Gebbia M, Prabha S, Gronda M, MacLean N, Wang X, Hurren R, Sukhai MA, Cho EE, Manolson MF, Datti A, Wrana J, Minden MD, Al-Awar R, Aman A, Nislow C, Giaever G, Schimmer AD. Select microtubule inhibitors increase lysosome acidity and promote lysosomal disruption in acute myeloid leukemia (AML) cells. Apoptosis. 2015 Jul;20(7):948-59. doi: 10.1007/s10495-015-1123-3. PubMed PMID: 25832785. |