| Description | Dentonin acetate enhances osteogenesis and facilitates immature adherent cell survival. Dentonin acetate, a synthetic fragment derived from MEPE, can be used in phosphate homeostasis and bone metabolism studies. |
| In vitro | Dentonin acetate （3-30 μg/ml；2-24小时）能显著促进成骨细胞的扩散。此外，Dentonin acetate （3-30 μg/ml；2-24小时）也显著增加了细胞数量，并增强了细胞粘附的促进作用。然而，就细胞粘附的数量而言，其与[1]中的其他处理没有显著差异。 |
| Synonyms | Dentonin acetate (400090-20-2 Free base) |
| molecular weight | 2598.64 |
| Molecular formula | C109H164N30O44 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 25.99 mg/mL (10 mM) |
| References | 1. N Six, et al. Dentonin, a MEPE fragment, initiates pulp-healing response to injury.J Dent Res. 2007 Aug;86(8):780-5. 2. Andrew P Sprowson, et al. ASARM-truncated MEPE and AC-100 enhance osteogenesis by promoting osteoprogenitor adhesion. J Orthop Res. 2008 Sep;26(9):1256-62. |