Description | Dehydrobruceine B, a quassinoid isolated from Brucea javanica, demonstrates a synergistic effect with Cisplatin in inducing apoptosis through the mitochondrial pathway. It enhances the expression of apoptosis-inducing factor (AIF) and Bax while inhibiting Keap1-Nrf2 [1]. |
molecular weight | 478.45 |
Molecular formula | C23H26O11 |
CAS | 53730-90-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |