| Description | Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload. |
| Synonyms | GT 56252, GT 56 252, 地夫立群, GT-56252, GT-56-252 |
| molecular weight | 253.27 |
| Molecular formula | C11H11NO4S |
| CAS | 239101-33-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 55 mg/ml (217.16 mM) |
| References | 1. Bergeron RJ, Wiegand J, Bharti N, McManis JS, Singh S. Desferrithiocin analogue iron chelators: iron clearing efficiency, tissue distribution, and renal toxicity. Biometals. 2011 Apr;24(2):239-58. Central PMCID: PMC3329216. 2. Bergeron RJ, Wiegand J, McManis JS, Bharti N, Singh S. Design, synthesis, and testing of non-nephrotoxic desazadesferrithiocin polyether analogues. J Med Chem. 2008 Jul 10;51(13):3913-23. 3. Barton JC. Drug evaluation: Deferitrin for iron overload disorders. IDrugs. 2007 Jul;10(7):480-90. PubMed PMID: 17642018. 4. Barton JC. Drug evaluation: deferitrin (GT-56-252; NaHBED) for iron overload disorders. IDrugs. 2007 Apr;10(4):270-81. Review. |