| Description | Dagrocorat is a novel and dissociated agonist of glucocorticoid receptor. |
| Target activity | CYP3A (human liver microsomes):1.3 μM (IC50), CYP2D6 (human liver microsomes):IC50 : 0.57 μM |
| Synonyms | PF-00251802 |
| molecular weight | 494.55 |
| Molecular formula | C29H29F3N2O2 |
| CAS | 1044535-52-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Ripp SL,et al. In Vitro and In Vivo Investigation of Potential for Complex CYP3A Interaction for PF-00251802 (Dagrocorat), a Novel Dissociated Agonist of the Glucocorticoid Receptor. Clin Pharmacol Drug Dev. 2018 Mar;7(3):244-255. |