| Description | Dacomitinib Intermediate 2 (N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine) has anticancer activity and can be used to study lung cancer. |
| Synonyms | N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine |
| molecular weight | 348.72 |
| Molecular formula | C15H10ClFN4O3 |
| CAS | 179552-74-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 16.67 mg/mL (47.79 mM), Sonication is recommended. |
| References | 1. Lanning BR, Whitby LR, Dix MM, Douhan J, Gilbert AM, Hett EC, Johnson TO, Joslyn C, Kath JC, Niessen S, Roberts LR, Schnute ME, Wang C, Hulce JJ, Wei B, Whiteley LO, Hayward MM, Cravatt BF. A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors. Nat Chem Biol. 2014 Sep;10(9):760-767. |