| Description | DA 5018 is a capsaicin derivative and is also a new non-narcotic analgesic. It has an antipruritic effect. |
| Synonyms | DA-5018, DA5018 |
| molecular weight | 406.95 |
| Molecular formula | C22H31ClN2O3 |
| CAS | 174661-97-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Kim DH, Ahn BO, Kim SH, Kim WB. Antipruritic effect of DA-5018, a capsaicin derivative, in mice. Arch Pharm Res. 1999 Dec;22(6):549-53. PubMed PMID: 10615858. 2. Kang YS, Kim JM. Permeability of a capsaicin derivative, [14C]DA-5018 to blood-brain barrier corrected with HPLC method. Arch Pharm Res. 1999 Apr;22(2):165-72. PubMed PMID: 10230507. 3. Lee JJ, Shim HJ, Kim SH, Lee SD, Kim WB, Yang J, Lee MG. Pharmacokinetics of a non-narcotic analgesic, DA-5018, in rats. Biopharm Drug Dispos. 1998 Mar;19(2):101-8. PubMed PMID: 9533110. 4. Shim HJ, Lee JJ, Lee SD, Kim WB, Yang J, Kim SH, Lee MG. Stability, blood partition, and protein binding of DA-5018, a new nonnarcotic analgesic. Res Commun Mol Pathol Pharmacol. 1996 Jan;91(1):97-108. PubMed PMID: 8824935. |