| Description | D4DAP is an inhibitor of HIV virus replication. |
| Synonyms | Ddedapr |
| molecular weight | 248.24 |
| Molecular formula | C10H12N6O2 |
| CAS | 109881-25-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Balzarini J, Robins MJ, Zou RM, Herdewijn P, De Clercq E. The 2',3'-dideoxyriboside of 2,6-diaminopurine and its 2',3'-didehydro derivative inhibit the deamination of 2',3'-dideoxyadenosine, an inhibitor of human immunodeficiency virus (HIV) replication. Biochem Biophys Res Commun. 1987 May 29;145(1):277-83. PubMed PMID: 3496090. 2. Balzarini J, De Clercq E. The antiviral activity of 9-beta-D-arabinofuranosyladenine is enhanced by the 2',3'-dideoxyriboside, the 2',3'-didehydro-2',3'-dideoxyriboside and the 3'-azido-2',3'-dideoxyriboside of 2,6-diaminopurine. Biochem Biophys Res Commun. 1989 Feb 28;159(1):61-7. PubMed PMID: 2538128. 3. Balzarini J, Pauwels R, Baba M, Robins MJ, Zou RM, Herdewijn P, De Clercq E. The 2',3'-dideoxyriboside of 2,6-diaminopurine selectively inhibits human immunodeficiency virus (HIV) replication in vitro. Biochem Biophys Res Commun. 1987 May 29;145(1):269-76. PubMed PMID: 3496089. |