| Description | D-Isoleucine ((2R,3R)-2-Amino-3-methylpentanoic acid) is a selective activator of Asc-1 antiporter, which enhances long-term potentiation at the hippocampal CA1-CA3 via release of endogenous D-serine. |
| Synonyms | (2R,3R)-2-Amino-3-methylpentanoic acid, D-异亮氨酸, (R)-Isoleucine |
| molecular weight | 131.17 |
| Molecular formula | C6H13NO2 |
| CAS | 319-78-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 55 mg/ml (419.3 mM) |
| References | 1. Rosenberg D, et, al. Neuronal D-serine and glycine release via the Asc-1 transporter regulates NMDA receptor-dependent synaptic activity. J Neurosci. 2013 Feb 20;33(8):3533-44. |