| Description | D595 is a phenethylamine-type calcium channel blocker. The most potent phenylethylamine with respect to negative inotropy was D595 (EC50: 794 nmol/l). |
| Synonyms | D595, D-595 |
| molecular weight | 463.44 |
| Molecular formula | C25H32Cl2N2O2 |
| CAS | 16740-29-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Clark JM, Brooks MW. Role of ion channels and intraterminal calcium homeostasis in the action of deltamethrin at presynaptic nerve terminals. Biochem Pharmacol. 1989 Jul 15;38(14):2233-45. PubMed PMID: 2546560. 2. Goll A, Glossmann H, Mannhold R. Correlation between the negative inotropic potency and binding parameters of 1,4-dihydropyridine and phenylalkylamine calcium channel blockers in cat heart. Naunyn Schmiedebergs Arch Pharmacol. 1986 Nov;334(3):303-12. PubMed PMID: 3027587. |