D-(-)-3-Phosphoglyceric acid disodium Bioactivity,Chemical Properties,Storage & Solubility Information Pathways-PeptideDB

Description	D-(-)-3-Phosphoglyceric acid disodium (3-Phospho-D-glyceric acid disodium) is an intermediate in several biological pathways, most notably glycolysis/gluconeogenesis and the biosynthesis of serine, glycine, and threonine, which competitively inhibits yeast enolase. It also has numerous roles as an intermediate in biosynthetic pathways in plants, eukaryotes, and prokaryotes.
In vitro	D-(-)-3-磷酸甘油酸二钠竞争性抑制酵母脱水酶。酶-Mg2+复合物与3-磷酸甘油酸进行热滴定。在相同的酶、金属和抑制剂浓度下，测量了3-磷酸甘油酸结合到脱水酶时吸收的热量，此实验在Tris、Hepes及Pipes中进行[1]。
Synonyms	3-Phospho-D-glyceric acid disodium
molecular weight	230.02
Molecular formula	C3H5Na2O7P
CAS	80731-10-8
Storage	store at low temperature\|Powder: -20°C for 3 years \| In solvent: -80°C for 1 year
Solubility	PBS (pH 7.2): 10 mg/mL H2O: 90.0 mg/mL (391.3 mM), Sonication is recommended.
References	1. Faller LD, et al. Calorimetric studies of the role of magnesium ions in yeast enolase catalysis. Proc Natl Acad Sci U S A. 1974 Apr;71(4):1083-7. 2. Ramos ML, et al. NMR and DFT studies of the complexation of W(VI) and Mo(VI) with 3-phospho-D-glyceric and 2-phospho-D-glyceric acids. Dalton Trans. 2009;(43):9616-9624.

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