| Description | Maculosin is a secondary metabolite of fungi and bacteria. |
| In vitro | Maculosin作为特异性植物毒素，在浓度为10μM时，能诱导 spotted knapweed (C. maculosa) 叶片形成泣痕状坏死斑点。同时，Maculosin在31.25μg/ml的最小抑菌浓度（MICs）下减缓了植物病原菌X. axonopodis和R. solanacearum的生长，以及在10到100 mg/ml的浓度范围内，也能抑制病原卵菌P. cactorum、P. capsici、P. cinnamomi、P. infestans和P. ultimum的发展。此外，当与pyrrolnitrin或banegasin结合使用时，Maculosin还能抑制M. luteus、M. smegmatis、S. cerevisiae、C. albicans、C. neoformans和A. niger的生长。 |
| molecular weight | 260.29 |
| Molecular formula | C14H16N2O3 |
| CAS | 4549-02-4 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 100 mg/mL (384.19 mM), Sonication is recommended. |
| References | 1. Stierle A C , Cardellina J H , Strobel G A . Maculosin, a host-specific phytotoxin for spotted knapweed from Alternaria alternata[J]. Proceedings of the National Academy of Sciences, 1988, 85(21):8008-8011. 2. Puopolo G , Cimmino A , Palmieri M C , et al. Lysobacter capsici AZ78 produces cyclo(L-Pro- L-Tyr), a 2,5-diketopiperazine with toxic activity against sporangia of Phytophthora infestans and Plasmopara viticola[J]. Journal of Applied Microbiology, 2014, 117(4). |