| Description | CUMI-101 is an agonist of 5-HT1A receptor. |
| molecular weight | 373.45 |
| Molecular formula | C19H27N5O3 |
| CAS | 179756-61-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Selvaraj S, Walker C, Arnone D, Cao B, Faulkner P, Cowen PJ, Roiser JP, Howes O. Effect of Citalopram on Emotion Processing in Humans: A Combined 5-HT(1A) [(11)C]CUMI-101 PET and Functional MRI Study. Neuropsychopharmacology. 2017 Aug 4. doi: 10.1038/npp.2017.166. [Epub ahead of print] PubMed PMID: 28776580; PubMed Central PMCID: PMC5693328. 2. Zanderigo F, Mann JJ, Ogden RT. A hybrid deconvolution approach for estimation of in vivo non-displaceable binding for brain PET targets without a reference region. PLoS One. 2017 May 1;12(5):e0176636. doi: 10.1371/journal.pone.0176636. eCollection 2017. PubMed PMID: 28459878; PubMed Central PMCID: PMC5411064. 3. Ganz M, Feng L, Hansen HD, Beliveau V, Svarer C, Knudsen GM, Greve DN. Cerebellar heterogeneity and its impact on PET data quantification of 5-HT receptor radioligands. J Cereb Blood Flow Metab. 2017 Sep;37(9):3243-3252. doi: 10.1177/0271678X16686092. Epub 2017 Jan 11. PubMed PMID: 28075185; PubMed Central PMCID: PMC5584698. 4. Schain M, Zanderigo F, Mann JJ, Ogden RT. Estimation of the binding potential BP(ND) without a reference region or blood samples for brain PET studies. Neuroimage. 2017 Feb 1;146:121-131. doi: 10.1016/j.neuroimage.2016.11.035. Epub 2016 Nov 14. PubMed PMID: 27856316. |