| Description | CTP-347, a deuterated version of paroxetine, is potentially the best non-hormonal drug in its class for the treatment of hot flashes. |
| Synonyms | CTP347, CTP 347 |
| molecular weight | 331.38 |
| Molecular formula | C19H20FNO3 |
| CAS | 923932-43-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Uttamsingh V, Gallegos R, Liu JF, Harbeson SL, Bridson GW, Cheng C, Wells DS, Graham PB, Zelle R, Tung R. Altering metabolic profiles of drugs by precision deuteration: reducing mechanism-based inhibition of CYP2D6 by paroxetine. J Pharmacol Exp Ther. 2015 Jul;354(1):43-54. doi: 10.1124/jpet.115.223768. Epub 2015 May 5. PubMed PMID: 25943764. |