| Description | CRANAD-2 is a difluoroboron-derivatized curcumins as near-infrared probe for in vivo detection of amyloid-beta deposits. Upon interacting with Abeta aggregates, CRANAD-2 undergoes a range of changes, which include a 70-fold fluorescence intensity increase, a 90 nm blue shift (from 805 to 715 nm), and a large increase in quantum yield. |
| molecular weight | 410.27 |
| Molecular formula | C23H25BF2N2O2 |
| CAS | 1193447-34-5 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 3.67 mg/ml |
| References | 1. Jara-Guajardo P , Cabrera P , Celis F , et al. Gold Nanoparticles Mediate Improved Detection of β-amyloid Aggregates by Fluorescence[J]. Nanomaterials, 2020, 10(4). |