| Description | CPA inhibitor (Carboxypeptidase inhibitor) is a potent carboxypeptidase A (CPA) inhibitor with a Ki of 0.32 μM. |
| Target activity | CPA:0.32 μM (Ki) |
| Synonyms | Carboxypeptidase inhibitor |
| molecular weight | 313.35 |
| Molecular formula | C18H19NO4 |
| CAS | 223532-02-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 90 mg/mL (287.2 mM), Sonication is recommended. |
| References | 1. D H Kim, et al. First hydroxamate inhibitors for carboxypeptidase A. N-acyl-N-hydroxy-beta-phenylalanines. Bioorg Med Chem Lett. 1999 Mar 8;9(5):691-6. 2. Zhang H, et al. Molecular dynamics and free energy studies on the carboxypeptidases complexed with peptide/small molecular inhibitor: mechanism for drug resistance.Insect Biochem Mol Biol. 2012 Aug;42(8):583-95. Epub 2012 Apr 23. 3. Kim, Dong H., et al. First hydroxamate inhibitors for carboxypeptidase A. N-acyl-N-hydroxy-beta-phenylalanines. Bioorganic & Medicinal Chemistry Letters (1999), 9(5), 691-696. |