| Description | CP-283097 is an N-methyl-D-aspartic acid (NMDA) receptor antagonist with NR2B subunit. |
| Synonyms | CP283097, UNII-WHL1Z3GN15, CP 283097 |
| molecular weight | 355.43 |
| Molecular formula | C21H25NO4 |
| CAS | 138047-56-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Murray F, Kennedy J, Hutson PH, Elliot J, Huscroft I, Mohnen K, Russell MG, Grimwood S. Modulation of [3H]MK-801 binding to NMDA receptors in vivo and in vitro. Eur J Pharmacol. 2000 Jun 2;397(2-3):263-70. PubMed PMID: 10844123. 2. Butler TW, Blake JF, Bordner J, Butler P, Chenard BL, Collins MA, DeCosta D, Ducat MJ, Eisenhard ME, Menniti FS, Pagnozzi MJ, Sands SB, Segelstein BE, Volberg W, White WF, Zhao D. (3R,4S)-3-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]chroman-4,7-diol: a conformationally restricted analogue of the NR2B subtype-selective NMDA antagonist (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)- 1-propanol. J Med Chem. 1998 Mar 26;41(7):1172-84. PubMed PMID: 9544217. |