| Description | Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5). |
| In vitro | Complement C5-IN-1与C5相互作用，抑制其被C5转化酶切割，并在50%的人全血中阻断酵母葡聚糖引发的膜攻击复合体（MAC）的沉积（IC50：0.77 µM）[1]。 |
| molecular weight | 444.52 |
| Molecular formula | C24H32N2O6 |
| CAS | 2365402-67-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 90mg/mL (202.5mM) |
| References | 1. Jendza K, et al. A small-molecule inhibitor of C5 complement protein. Nat Chem Biol. 2019 Jul;15(7):666-668. |