| Description | Collagenase Type I is a proteolytic enzyme that breaks down the peptide bonds in collagen, the main structural protein of connective tissue. Collagenase has been explored as a potential treatment option to break down herniated disc material, thereby reducing pressure on nearby nerves. Collagenase may aid in the breakdown and reorganization of excessive scar tissue, potentially improving tissue function and appearance. Collagenase has the potential to treat disc herniation, keloid, cellulite, lipoma, as well as Peroni's disease and palm fibromatosis. |
| Synonyms | Collagenase I, Collagenase Type I (From microorganisms) |
| molecular weight | N/A |
| CAS | 9001-12-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Tchetina EV,et al. Chondrocyte hypertrophy can be induced by a cryptic sequence of type II collagen and is accompanied by the induction of MMP-13 and collagenase activity: implications for development and arthritis. Matrix Biol. 2007;26(4):247-258. 2. Qiao J, et al. A rabbit model of corneal Ectasia generated by treatment with collagenase type II. BMC Ophthalmol. 2018;18(1):94. |