| Description | Collagen-IN-1 (compound 3) is an ortho-carbonyl hydroquinone derivative exhibiting selective inhibition of collagen. It non-competitively inhibits agonist-induced platelet aggregation, with an IC50 value of 1.77 μM. Collagen-IN-1 effectively reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelets. This compound holds promise for research into platelet-related thrombosis diseases [1]. |
| molecular weight | 230.26 |
| Molecular formula | C14H14O3 |
| CAS | 104260-73-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |