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Cochinchinenin A

CAS No.: 1057666-04-2

Cochinchinenin A is the material basis for the analgesic effect of Dragons Blood.
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Description Cochinchinenin A is the material basis for the analgesic effect of Dragons Blood.
In vitro 根据中药功效物质基础的操作定义,通过实验结果评判了龙血的TTX-R钠电流调控物质基础。采用Greco等人的化合物相互作用方程,评估了从龙血中提取的三个成分的相互作用。研究表明,龙血以剂量依赖性方式抑制TTX-R钠电流峰值,并影响TTX-R钠电流的激活。Cochinchinenin A、Cochinchinenin B和Loureirin B的组合效果与龙血的效果高度一致。尽管三个成分单独使用能够调节TTX-R钠电流,但在单独使用和联合使用时达到相同的TTX-R钠电流抑制率,三个成分单独使用的浓度分别高于联合使用。这三个成分的联合效应是协同的。
molecular weight 286.32
Molecular formula C17H18O4
CAS 1057666-04-2
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility DMSO: 22.5 mg/mL (78.58 mM)
References 1. Modulation of dragon€™s blood on tetrodotoxin-resistant sodium currents in dorsal root ganglion neurons and identification of its material basis for efficacy Science in China Series C June 2006, Volume 49, Issue 3, pp 274-285