| Description | CNX-1351 is a potent and isoform-selective targeted covalent PI3Kα inhibitor. |
| Target activity | PI3Kα:6.8 nM |
| Synonyms | 1-[4-[[2-(1H-吲唑-4-基)-4-(4-吗啉基)噻吩并[3,2-D]嘧啶-6-基]甲基]-1-哌嗪基]-6-甲基-5-庚烯-1,4-二酮 |
| molecular weight | 573.71 |
| Molecular formula | C30H35N7O3S |
| CAS | 1276105-89-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 5.73 mg/mL (9.99 mM) |
| References | 1. Nacht M, et al. J Med Chem. 2013 Feb 14;56(3):712-21. |