| Description | Clidanac is a potent anti-inflammatory drug and is found to uncouple the oxidative phosphorylation. |
| Synonyms | Clidanaco, TAI 284, Britai, TAI-284, TAI284 |
| molecular weight | 278.77 |
| Molecular formula | C16H19ClO2 |
| CAS | 34148-01-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Kawai K, Shiojiri H, Fukushima H, Nozawa Y, Hasegawa J, Nozaki M, Tsurumi K, Fujimura H. The effect of clidanac, a potent anti-inflammatory drug, on mitochondrial respiration: a consideration on the uncoupling activity of optical enantiomers. Res Commun Chem Pathol Pharmacol. 1984 Sep;45(3):399-406. PubMed PMID: 6334337. 2. Boettcher I, Elger W, Kirsch G, Siegmund F, Wachtel H. Nonsteroidal antiinflammatory agents. 14. Synthesis and pharmacological profile of 6-chloro-5-(cyclopentylmethyl)indan-1-carboxylic acid. J Med Chem. 1984 Mar;27(3):413-4. PubMed PMID: 6608000. 3. Hasegawa J, Nozaki M, Fujimura H. [The effects of various drugs on the binding site of bilirubin in serum albumin]. Nihon Yakurigaku Zasshi. 1984 Jan;83(1):79-83. Japanese. PubMed PMID: 6714852. 4. Hutt AJ, Caldwell J. The metabolic chiral inversion of 2-arylpropionic acids--a novel route with pharmacological consequences. J Pharm Pharmacol. 1983 Nov;35(11):693-704. Review. PubMed PMID: 6139449. |